While short-term usage might only produce small, short-term impacts in the brain, extended compound usage changes the brain in essential methods that reinforce continued use, such as the strengthening of memory circuits associated with drug taking. Hints that are social (such as being around substance-using buddies), geographic (previous preferred bars), and physical (experiencing tension) in nature become highly related to the drug.Brain changes from chronic drug or alcohol use can continue years after a person gives up. This is why individuals risk regression even after extended periods of abstaining, and despite a relapse's possibly terrible effects. More importantly, this is why treatment depends upon the kind of drug and the individual attributes of the client.