And of course you will most likely acquire a different cold, since there are more than several hundred different cold viruses. Yet you will certainly never acquire the very same runny nose infection that you had previously because you have created immunity to that particular cold virus.Human papilloma virus is similar in that HPV is just an additional viral infection. And you can most likely develop resistance to HPV. Nevertheless, human papilloma virus is more capable at concealing from your body's immune system than are the cold infections. Moreover you have to work with more diligence to get resistance to HPV.